Single-Dose Intra-Operative Radiation Therapy for Breast Cancer: 2015 Top 10 Medical Innovation Finding and treating breast cancer in its earliest stages can oftentimes lead to a cure. For most women with early-stage breast cancer, a lumpectomy is performed followed by weeks of radiation therapy to reduce the likelihood of recurrence. Intra-operative radiation therapy, or IORT, focuses the radiation on the tumor during surgery as a single-dose, and has proven effective as whole breast radiation. For more information about Medical Innovation Summit, visit