Smoothened Inhibitors in Sonic Hedgehog Subgroup Medulloblastoma

Understanding the Pathway article: http://ascopubs.org/doi/full/10.1200/JCO.2015.62.2225

The Journal of Clinical Oncology’s “Understanding the Pathway” articles accompany an Original Report and describe the underlying pathway or biological process, explain its relevance to the original report, and highlight future therapeutic or investigational directions pertaining to the pathway in cancer.