Lung cancer symptoms: What to know Patients with early-stage lung cancer may not experience any noticeable symptoms. But, as the cancer progresses, they may experience side effects like shortness of breath, unexplained coughing, chest pain and bloody coughs. Other symptoms may include weight loss, pain in the shoulders or back and fatigue. Dennis Nader, DO, FCCP, Director of the Lung Center at Cancer Treatment Centers of America (CTCA) in Tulsa, Oklahoma, lists other common signs and symptoms for lung cancer. To learn more about lung cancer symptoms and available treatment options visit