How Xgeva ( Denosumab ) Treats Bone Metastases Xgeva (Denosumab) is an FDA approved targeted cancer treatment that is used to help prevent bone fractures and other skeletal conditions that may occur in patients with certain metastatic cancers, such as breast cancer or prostate cancer, where the cancer has spread to the bones. In this video, oncologist Stephen Lemon MD explains how this cancer treatment works and what types of side effects may occur. Visit to learn more about Xgeva (Denosumab) and its side effects. Dr. Lemon is a board certified oncologist for Omaha based Oncology Associates. He is not affiliated with Amgen, who produces Xgeva (Denosumab). These videos are intended to provide information on new and existing cancer treatments, including their side effects. Visit to learn more about Oncology Associates and their approach to personalized cancer treatment.