Eliminating Pediatric Cancer Using T-Cell Immunotherapy

Dr. Michael Jensen, Center Director of Seattle Children’s Research Institute’s Ben Towne Center for Childhood Cancer Research, gives a talk on Seattle Children’s work to eradicate pediatric cancer through an innovative new treatment called immunotherapy.

Using this therapy, researchers reprogram a child’s own immune cells, or T cells, to find and destroy cancerous cells – without the devastating effects of chemotherapy and radiation.

Seattle Children’s scientists have successfully reprogrammed T cells in patients with acute lymphoblastic leukemia (ALL) to find and destroy cancer cells, as part of a Phase 1 clinical trial.

Based on the positive results with this therapy thus far, Seattle Children’s is now the first center in the United States to begin a phase 1 immunotherapy clinical trial for children with relapsed or treatment unresponsive neuroblastoma.

Clinical trials currently enrolling participants:
• T-Cell Therapy Clinical Trial for Leukemia
• http://www.seattlechildrens.org/clinics-programs/cancer/research-and-advances/clinical-trials/t-cell-therapy-leukemia/
• Call 206-987-2106 or email immunotherapy@seattlechildrens.org

• T-Cell Therapy Clinical Trial for Neuroblastoma
• Call 206-987-2106 or email immunotherapy@seattlechildrens.org

• About Seattle Children’s Research Institute’s Ben Towne Center for Childhood Cancer Research: http://www.seattlechildrens.org/research/childhood-cancer/

• About Seattle Children’s Research Institute’s Center for Clinical and Translational Research: http://www.seattlechildrens.org/research/clinical-and-translational-research/

• About Seattle Children’s Cancer and Blood Disorders Center: http://www.seattlechildrens.org/cancer/