Cancer Is a Laughing Matter | Karen Mills | TEDxChattanooga Karen’s annual trip to the gynecologist started as an ordinary day. There was no reason to suspect that her checkup would be anything other than routine. Being a comedian, Karen had always looked for the humor in life and encouraged others to do the same; attitude, she’d told everyone, was everything. Her mantra was to stay positive and find the silver lining because humor was healing and laughter, the best medicine. Now, though faced with ovarian cancer, could Karen do more than talk the talk? Can cancer really be a laughing matter? Karen Mills has made a career out of making people laugh. She’s been a nationally touring comedian for 23 years and can be heard daily on Sirius/XM comedy channels. Diagnosed in 2013 after a routine checkup, Mills was determined to take on the disease with hope and humor. Her mission is to inspire people to love, laugh, and approach everything life hands you with a positive attitude. Now cancer-free, she has been hailed for her ability to bring humor and inspiration to difficult topics as she did recently when she spoke at the Ovarian Cancer National Alliance in Washington, D.C. This talk was given at a TEDx event using the TED conference format but independently organized by a local community. Learn more at